Case Reports in Clinical Practice 2016. 1(1):11-14.

Hashimoto Encephalopathy with Sensory Polyneuropathy: A Case Report
Hamed Cheraghmakani, Mahmoud Abedini, Abdorreza Naser Moghadasi


Hashimoto encephalopathy is an autoimmune disease characterized by an increase in antithyroid antibodies in the serum of patients with multiple neuropsychological symptoms. We report a case with lower level of antibody and fairly response to corticosteroid; however, clinical presentation, brain magnetic resonance imaging findings and the negative results of other diseases confirmed Hashimoto encephalopathy diagnosis. First, a relatively good corticosteroid response was seen but after one weak, the patient withdrew her drug and got back with a corticosteroid resistant progressive attack one month later. Our case had a mild increase in antithyroid antibodies and pure sensory polyneuropathy and did not show significant response to corticosteroid therapy. Can antithyroid antibodies titers be a marker of corticosteroid treatment response? this should be investigated in the future studies.


Antithyroid antibody; Hashimoto encephalopathy; Polyneuropathy

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