Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 2 1 2017 08 26 16 20 EN Mohammad Tajdini Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Mansoureh Shariat Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammadreza Mizaaghayan Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Sara Memarian Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Parisa Rahmani Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammadtaghi Majnoon Department of Pediatrics, School of Medicine, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. 2017 03 02 2017 06 07 This report describes two patients (a 7-year-old boy and a 3-month-old boy) who have had chronic and recurrent respiratory distress and wheezing episodes since infancy. The elder one had been treated for hyper-reactive airway disease and asthma, and the other had been diagnosed with laryngomalacia. The problems had been associated with cyanosis and did not improve with routine treatment; therefore, we considered other underlying diseases, such as cardiovascular problems. The diagnostic workups revealed the “double aortic arch” which had not been diagnosed previously. https://crcp.tums.ac.ir/index.php/crcp/article/view/106 https://crcp.tums.ac.ir/index.php/crcp/article/download/106/68