Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 11 1 2026 08 03 4 8 EN Rahime Eskandarian Department of Cardiology, Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran. Mohammad Sadegh Vashveshady Department of Cardiology, Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran. Maryam Ezzedin Department of Anesthesiology, Clinical Research Development Unit, Kowsar Educational, Research and Therapeutic Hospital, Semnan University of Medical Sciences, Semnan, Iran. 2025 08 31 2026 05 20 Port catheters are recommended for patients requiring long-term intravenous therapy, particularly in cancer patients who are debilitated and require administration of chemotherapy or cytotoxic drugs. Mechanical complications of port placement include port occlusion, displacement, and catheter fracture. In this case report, we present the endovascular retrieval of a fractured chemotherapy port catheter fragment from the superior vena cava using a snare device. A 60-year-old woman with metastatic breast cancer presented with infusion difficulty through her 18-monthold subclavian chemotherapy port. The surgeon noticed that the port had not been fully extracted, prompting an urgent consultation for intervention. Fluoroscopyguided retrieval of an SVC catheter fragment was achieved via femoral access using an Amplatz snare after failed EN Snare attempts. The patient was discharged postprocedure without complications. Proactive chemotherapy port surveillance enables early complication management. Catheter fractures necessitate multidisciplinary care, where endovascular snare retrieval augmented by surgical excision demonstrates optimal safety and efficacy. https://crcp.tums.ac.ir/index.php/crcp/article/view/1095 https://crcp.tums.ac.ir/index.php/crcp/article/download/1095/768