Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 10 4 2026 04 18 147 153 Ahmadreza Rajabi School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Hanie Forouzandeh School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Abbas Ali Torfeh Esfandi Department of Infectious Diseases and Tropical Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Golnaz Khorasanizadeh Department of Infectious Diseases and Tropical Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. 2025 09 24 2025 12 17 Mucormycosis is an invasive fungal infection caused by fungi of the order Mucorales. It can lead to significant mortality and morbidity in immunocompromised and diabetic patients. We herein present a patient with untreated type 2 diabetes who was admitted for acute progressive vision loss. Following diagnostic findings, she was diagnosed with mucormycosis that directly infiltrated the cerebral arteries, resulting in blindness in her left eye. This is an uncommon presentation of mucormycosis, as it led to arterial invasion without involving the orbit. This case underscores the significance of promptly diagnosing mucormycosis in susceptible individuals to avert catastrophic outcomes. https://crcp.tums.ac.ir/index.php/crcp/article/view/1101 https://crcp.tums.ac.ir/index.php/crcp/article/download/1101/736