Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 11 3 2026 09 28 126 132 Prerna Walia Department of Oncopathology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India. Nandlal Bharwani Orthopedic Oncology Unit, Department of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India. Hemant Saraiya Plastic Surgery Unit, Department of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India. Abhijeet Salunke Orthopedic Oncology Unit, Department of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India. 2026 06 12 2026 06 29 Eccrine poroma (EP) is a benign skin adnexal tumor that originates from eccrine sweat glands. It usually appears as a solitary mass on an extremity, commonly on the hand or foot. However, clinical presentation can be varied, posing diagnostic challenges. This study describes a rare case of ulcerative EP on the palm. It covers the clinical and histological features, the diagnostic and treatment approaches, and the potential for local recurrence or malignant transformation. https://crcp.tums.ac.ir/index.php/crcp/article/view/1204 https://crcp.tums.ac.ir/index.php/crcp/article/download/1204/793