Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 2 3 2018 02 17 67 70 EN Saeid Rezaei Jouzdani Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Bahram Pakzad Associate Professor, Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. 2017 08 17 2017 10 29 Kawasaki disease is a rheumatologic disorder that is due to small- to medium-sized vessels necrotizing vasculitis with unknown origin. The disease affects children predominantly, but rarely occurs in adults. We report a case of 23-year-old woman from Iran who had got high grade fever, bilateral non-purulent conjunctivitis, myalgia, palms and soles exanthema, and desquamation. After 5 days of empirical antibiotic therapy without any organisms identified for source of infection, the diagnosis was established. No treatment with intravenous gammaglobulin and aspirin was administered and her echocardiogram showed normal coronary arteries. The age of our patient is an unusual aspect of the disease presentation in Iran. The diagnosis of Kawasaki in adults should be considered in patients with prolonged fever not responding to antibiotics with clinical features of Kawasaki disease. https://crcp.tums.ac.ir/index.php/crcp/article/view/128 https://crcp.tums.ac.ir/index.php/crcp/article/download/128/81