Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 3 1 2018 07 24 Esophageal Squamous Cell Carcinoma Presenting as Two Simultaneous Adjacent Masses Confirmed by Pathologic Findings: Report of a Rare Case 21 25 EN Hamidreza Khorshidi Department of General Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Mehrdad Taghipour Department of General Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Babak Yousefi Department of General Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Arash Dehghan Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. 2018 02 03 2018 05 20 Esophageal squamous cell carcinoma (SCC) is a common neoplasm which incidence shows an increasing trend in most populations. This article presents a case of 79-year-old woman with diagnosis of differentiated squamous cell carcinoma of the esophagus as two adjacent mas with metastasis, which invaded the perigastric and distal esophagus lymph nodes. The patient underwent esophagectomy and gastroesophagotomy. The jejunostomy tube was also embedded. The presence of two simultaneous esophageal tumoral lesions is extremely uncommon and requires further assessments. The prognosis and survival of such patients not seems to be worse than those of patients with isolated esophageal neoplasm. https://crcp.tums.ac.ir/index.php/crcp/article/view/179 https://crcp.tums.ac.ir/index.php/crcp/article/download/179/102