Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 3 2 2018 12 24 59 61 EN Nooshin Shirzad Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran, Department of Endocrinology, Vali Asr Hospital, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mahboobeh Hemmatabadi Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran 2- Department of Endocrinology, Vali Asr Hospital, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran. Arezoo Saeedinia Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran. Hoda Rashidian Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, IranEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Science Institute, Tehran University of Medical Sciences, Tehran, Iran. 2018 05 18 2018 07 28 A 30-year-old woman with a 20-year history of type 1 diabetes referred to our clinic with the complaints of facial acne, hirsutism, and irregular menstrual cycles (hirsutism was identified in physical examination). On biochemical analysis, high serum levels of antiTPO and DHEA-S were detected. Based on ultrasonographic findings indicative of thyroiditis and positive anti-TPO test, the diagnosis of Hashimoto's thyroiditis was made. A diagnosis of Polycystic Ovary Syndrome (PCOS) was confirmed later according to the Rotterdam criteria (revised 2003). The patient received metformin and insulin for 3 months and her menstrual cycles became regular. https://crcp.tums.ac.ir/index.php/crcp/article/view/196 https://crcp.tums.ac.ir/index.php/crcp/article/download/196/285