Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 1 2 2016 09 24 54 57 EN Taraneh Dormohammadi Toosi Department of Rheumatology, Vali Asr Hospital, Imam Khomeini Hospital Complex AND Center for Research on Occupational Disease, Tehran University of Medical Sciences, Tehran, Iran Abdorahman Rostamian Department of Rheumatology, Vali Asr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Ali Khalvat Department of Rheumatology, Vali Asr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Fatemeh Shahbazi Department of Rheumatology, Vali Asr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences AND Department of Biology, Payame Noor University, Tehran, Iran 2015 12 28 2016 02 27 Systemic lupus erythematosus (SLE) is a chronic inflammatory disorderwith unknown etiology which can involve various organs in the body. The most common symptoms of this disease are constitutional symptoms along with skin rashes, arthritis, nephrologic, and hematologic manifestations. Acute pancreatitis is an unusual presentation of SLE. Here, we report an interesting case SLE who suffered from fever, weakness, abdominal pain, and weight loss. Finally, lupuspancreatitis was diagnosed based on her symptoms, laboratory, and imaging findings. https://crcp.tums.ac.ir/index.php/crcp/article/view/20 https://crcp.tums.ac.ir/index.php/crcp/article/download/20/23