Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 1 1 2016 01 20 1 3 EN Maryam Edalatifard Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Roghayeh Marandi Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Mohammad Afzalimoghaddam Department of Emergency Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Nasim Khajavirad Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 01 20 2016 01 20 A 53-year-old obese woman with history of obsessive compulsive disorder was referred to the general internal medicine clinic because of erythroderma and progressive dyspnea. Tapering psychiatric drugs and administering corticosteroids did not help her. A mild exudative pleural effusion and solid/cystic large ovarian masses were found in work-ups. The pathology of the masses was indicative of high-grade serous adenocarcinoma of ovaries. Five months after surgery and chemotherapies, her erythroderma resolved, confirming the diagnosis of paraneoplasric erythroderma due to ovarian cancer. https://crcp.tums.ac.ir/index.php/crcp/article/view/21 https://crcp.tums.ac.ir/index.php/crcp/article/download/21/1