Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 4 4 2020 04 30 102 104 Saeideh Salehizadeh Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. Abdorreza Naser Moghadasi Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. 2019 04 21 2019 07 28 In this case study, we presented the radiological characteristics of a 43-year-old female patient diagnosed with Multiple Sclerosis (MS). Following mitoxantrone administration, she developed liver failure. Magnetic Resonance Imaging (MRI) revealed multiple periventricular lesions in T2 and bilateral involvement of putamen and Globus Pallidus (GP) areas in T1 sequences. https://crcp.tums.ac.ir/index.php/crcp/article/view/263 https://crcp.tums.ac.ir/index.php/crcp/article/download/263/329