Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 1 1 2016 01 20 25 27 EN Violet Zaker-Esteghamati Department of Internal Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Seyyed Farshad Allameh Department of Internal Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Soheil Peiman Department of Internal Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran 2016 01 20 2016 01 20 Leptospirosis  is  a  common  zoonotic  infection  in  human  caused  by spirochete Leptospira. The disease is often underdiagnosed because of the difficulties in its clinical diagnosis and lack of suitable confirmatory laboratory tests. In this case report, we describe a case which highlights the importance of considering leptospirosis as the diagnostic possibility with hepatic, renal, and hematologic system involvement particularly where diagnostic support and resource are limited. https://crcp.tums.ac.ir/index.php/crcp/article/view/28 https://crcp.tums.ac.ir/index.php/crcp/article/download/28/8