Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 5 4 2021 01 16 121 123 Behshad Pazooki Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Shahrzad Shojaie Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. 2020 05 24 2020 07 03 Reactive arthritis is clinically defined as inflammatory aseptic arthritis which develops shortly after an extra-articular infection. The classic triad of conjunctivitis, urethritis, and arthritis is found in a minority of patients. Patiepresent with an asymmetric mono- or oligoarthritis that predominantly affect lower limbs. Here, we present a case of reactive arthritis with inadequate primary response to Nonsteroidants Usually  l Non-SteroidalAnti-inflammatory Drugs (NSAIDs).  https://crcp.tums.ac.ir/index.php/crcp/article/view/357 https://crcp.tums.ac.ir/index.php/crcp/article/download/357/373