Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 6 2 2021 08 07 66 69 EN Maryam Karimi Fard Non-communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Mehdi kafi Student Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. 2020 07 13 2020 08 04 Hypoparathyroidism is an endocrine disorder that can be congenital or acquired. Generally, hypoparathyroidism is characterized by hypocalcemia, hyperphosphatemia, and low or abnormal levels of Parathyroid Hormone (PTH). It can be asymptomatic or symptomatic. The symptoms include seizures, paresthesia, depression, psychosis, extrapyramidal manifestations, and increased intracranial pressure. In this case study, we reported a 40-year- old male patient who was admitted to the emergency department with generalized tonic- clonic movements and urine incontinency. Laboratory investigations revealed hypocalcemia, hyperphosphatemia, and low parathyroid hormone levels and in paraclinical studies, including Electroencephalography (EEG) and brain CT-scan, despite normal EEG, extensive intracranial calcification involving the basal ganglia, thalamus, white matter of the cerebral hemispheres, and subcortical area of the frontal and parietal lobes were observed on CT-scan. https://crcp.tums.ac.ir/index.php/crcp/article/view/374