Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 6 4 2021 11 27 Pitfalls in the Histopathologic Diagnosis of Meningioma: Report of Three Rare Variants of Meningioma and Literature Review 173 180 Ghazaleh Shaker Department of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Farid Azmoudeh Ardalan Department of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Mehdi Zeinalizadeh Department of Neurological Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. 2020 10 22 2020 12 13 Meningioma is a common primary tumor of the central nervous system and one of the most encountered brain tumors. Although classic histopathologic features of meningioma are relatively common and make its diagnosis straightforward, certain variants possess unusual histologic features causing diagnostic challenges. We reported three cases of clear cell meningioma, microcytic meningioma, and angiomatous meningioma report, variants with potential deceptive morphologies, and discuss their distinguishing morphologic features. https://crcp.tums.ac.ir/index.php/crcp/article/view/414