Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 6 5 2022 01 17 185 188 Saeed Farzanehfar Department of Nuclear Medicine, Vali-AsrHospital, Tehran University of Medical Sciences, Tehran, Iran. Arefeh Mirzabeigi Research Institute in Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Nafise Ghalandari Department of Nuclear Medicine, Vali-AsrHospital, Tehran University of Medical Sciences, Tehran, Iran. Mehrshad Abbasi Department of Nuclear Medicine, Vali-AsrHospital, Tehran University of Medical Sciences, Tehran, Iran. 2020 10 27 2020 12 13 A 41-year-old female with retractable epigastric pain due to an invasive neuroendocrine tumor of the pancreas was treated with blockage and radiofrequency ablation of the celiac and splanchnic plexuses. Then, the patient developed back pain, and a bone scan revealed abnormal uptake in the lower thoracic vertebrae despite a normal CT scan. The findings were interpreted as a local invasion of the tumor or iatrogenic post-manipulation inflammation or infection. MRI data presented the destruction of the thoracic 11th and 12th vertebrae, and pathology examination of the open biopsy sample favored inflammatory changes. https://crcp.tums.ac.ir/index.php/crcp/article/view/416