Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 7 4 2023 01 07 167 171 EN Ebrahim Farashi Department of Cardiothoracic Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. Seyed Ziaeddin Rasihashemi Department of Cardiothoracic Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. Monireh Halimi Department of Pathology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. 2021 04 16 2021 10 03 Adrenal ganglioneuromas are rare benign and non-secretory neoplasms that, in the majority of cases, are unexpectedly discovered during imaging studies. In this study, we reported a large adrenal ganglioneuromas in a young patient, clinically presented as a pheochromocytoma. Laboratory evaluation and tumor markers were also report- ed in the normal range. The mass was then resected through laparoscopy. Ultimate- ly, histopathology revealed the diagnosis of Ganglioneuroma. Large adrenal gangli- oneuromas can be resected laparoscopically without any complications. An accurate pathological examination is usually essential for definitive diagnosis. Prognosis of ma- ture adrenal ganglioneuromas is excellent. https://crcp.tums.ac.ir/index.php/crcp/article/view/515