Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 7 4 2023 01 07 211 215 Reza Taslimi Department of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. Taha Bayat Iranian Medical Students’ Association (IMSA-Iran), Students’ Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran. Behshad Pazooki Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Seyed Ali Nabipoorashrafi Department of Internal Medicine, Iran University of Medical Sciences, Tehran, Iran. 2022 02 26 2022 06 01 Salmonella typhi is the cause of an acute febrile illness with high morbidity and mortality, especially in countries with poor sanitation. Neurological complications of salmonella are severe and usually under-diagnosed. This article reports an extremely rare case of a woman with typhoid fever with a history of travel and consumption of raw fish. She had no sign of meningitis but developed diplopia and sixth nerve palsy, which was ultimately resolved by antibiotic therapy. https://crcp.tums.ac.ir/index.php/crcp/article/view/661