Tehran University of Medical Sciences Case Reports in Clinical Practice 2538-2683 8 4 2024 01 09 143 145 shaghayegh Ashraf Talesh Department of Infectious Diseases, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran Azar Hadadi Department of Infectious Diseases, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran 2023 04 29 2023 08 15 Immune thrombocytopenic purpura (ITP) is a condition that can occur either spontaneously or as a secondary complication of preexisting disorders, often associated with viral infections. In the context of COVID-19, hematological manifestations, including thrombocytopenia, have been observed and linked to increased mortality rates among severely infected patients.Presented here is a case study of a 70-year-old man who recovered from COVID-19 but subsequently developed ITP. The severity of his thrombocytopenia exceeded what is typically observed during COVID-19 infections, leading to a diagnosis of ITP. Treatment with steroids and intravenous immunoglobulin (IVIG) was initiated based on specialist recommendations, resulting in an adequate response. https://crcp.tums.ac.ir/index.php/crcp/article/view/819