An Immunocompetent Man with Pulmonary Nocardiosis
AbstractNocardia infections rarely occur among normal population. Nocardiosis typically develops in immunocompromised person. In this paper, we report a case of pulmonary nocardiosis in an immunocompetent man. A 77-year-old man was examined in the emergency department because of cough, sputum, and fever from 10 days before admission. Computed tomography (CT) of the chest revealed air space consolidation, necrosis and cavities. Positive culture for nocardia species was reported. The patient received cotrimoxazole two regular-strength tablets (400/80 mg) "per os" (P.O) every 12 hours, and was discharged. In the follow-up after a month, he was completely well, most of his symptoms were improved, and his chest CT was near normal.
Krucik G. Nocardia infection (Nocardiosis) [Online]. [cited 2016]; Available from: URL: https://www.healthline.com/health/nocardiainfection.
Beaman BL, Burnside J, Edwards B, Causey W. Nocardial infections in the United States, 1972-1974. J Infect Dis 1976; 134(3): 286-9.
Yasar Z, Acat M, Onaran H, Ozgul MA, Fener N, Talay F, et al. An unusual case of pulmonary nocardiosis in immunocompetent patient. Case Rep Pulmonol 2014; 2014: 963482.
Uttamchandani RB, Daikos GL, Reyes RR, Fischl MA, Dickinson GM, Yamaguchi E, et al. Nocardiosis in 30 patients with advanced human immunodeficiency virus infection: Clinical features and outcome. Clin Infect Dis 1994; 18(3): 348-53.
Singh I, West FM, Sanders A, Hartman B, Zappetti D. Pulmonary nocardiosis in the immunocompetent host: Case series. Case Rep Pulmonol 2015; 2015: 314831.
Long PF. A retrospective study of Nocardia infections associated with the acquired immune deficiency syndrome (AIDS). Infection 1994; 22(5): 362-4.
Aidê MA, Lourenço SS, Marchiori E, Zanetti G, Mondino PJ. Pulmonary nocardiosis in a patient with chronic obstructive pulmonary
disease and bronchiectasis. J Bras Pneumol 2008; 34(11): 985-8.
Hizel K, Caglar K, Cabadak H, Kulah C. Pulmonary nocardiosis in a non-Hodgkin's lymphoma patient. Infection 2002; 30(4): 243-5.
Feigin DS. Nocardiosis of the lung: Chest radiographic findings in 21 cases. Radiology 1986; 159(1): 9-14.
Menendez R, Cordero PJ, Santos M, Gobernado M, Marco V. Pulmonary infection with Nocardia species: A report of 10 cases and review. Eur Respir J 1997; 10(7): 1542-6.
Fujita T, Ikari J, Watanabe A, Tatsumi K. Clinical characteristics of pulmonary nocardiosis in immunocompetent patients. J Infect Chemother 2016; 22(11): 738-43.
Wilson JW. Nocardiosis: Updates and clinical overview. Mayo Clin Proc 2012; 87(4): 403-7.
Lerner PI, Baum GL. Antimicrobial susceptibility of Nocardia species. Antimicrob Agents Chemother 1973; 4(2): 85-93.
Saubolle MA, Sussland D. Nocardiosis: Review of clinical and laboratory experience. J Clin Microbiol 2003; 41(10): 4497-501.
Bennett JE, Dolin R, Blaser MJ. Mandell, douglas, and bennett's principles and practice of infectious diseases. Philadelphia, PA: Saunders; 2014.
Tunkel AR, Crane JK, Hayden FG. Pulmonary nocardiosis in AIDS. Chest 1991; 100(1): 295-6.