Amyloidosis With Periorbital Rash

  • morteza daraei Department of Internal Medicine, resident of Imam khomeini Hospital, University of Medical Sciences
  • Goli Siri Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran
  • Seyed Farshad Allameh Department of Internal Medicine, Imam khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • samira Alesaeidi First affiliation: Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Second affiliation: Department of Rheumatology, Internal Medicine, Amiralam research center, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Keywords: Amyloidosis;, Congo red;, Duodenal biopsy

Abstract

We presented a middle-aged woman with nonspecifc signs and symptoms, including dyspnea, lower limb edema, and elevated jugular venous pressure. Among these, the skin changes including nail changes, macroglossia and periorbital rash were the mos important clues to suspect primary amyloidosis. Paraclinical sudies were anemia, proteinuria and resricted cardiomyopathy. Abdomi nal fat pad biopsy is usually the frs sep to confrm the amyloidosis. However, despite the negative hisologic result of fat-pad biopsy, we performed duodenal biopsy that confrmed amyloidosis. This case report demonsrates the important value of duodenal tissue in order to conform the diagnosis of amyloidosis.

Author Biography

morteza daraei, Department of Internal Medicine, resident of Imam khomeini Hospital, University of Medical Sciences
first author for contact

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Published
2019-01-16
How to Cite
1.
daraei morteza, Siri G, Allameh SF, Alesaeidi samira. Amyloidosis With Periorbital Rash. CRCP. 3(3):79-2.
Section
Case Report(s)