Ventricular Tachyarrhythmia after Sildenafil Intake: A Case Report
Abstract
This study reports the occurrence of ventricular tachyarrhythmia after sildenafil (Viagra®) intake. A 60-year-old man was admitted to the hospital with ventricular arrhythmia after sildenafil (Viagra®) intake. The echocardiography was normal, but in angiography, mild atherosclerotic plaques were seen. Comprehensive clinical trials are needed to prove any correlation between sildenafil intake and acute myocardial infarction.
Porter A, Mager A, Birnbaum Y, Strasberg B, Sclarovsky S, Rechavia E. Acute myocardial infarction following sildenafil citrate (Viagra)
intake in a nitrate-free patient. Clin Cardiol 1999; 22(11): 762-3.
Kekilli M, Beyazit Y, Purnak T, Dogan S, Atalar E. Acute myocardial infarction after sildenafil citrate ingestion. Ann Pharmacother 2005; 39(7-8): 1362-4.
Kloner RA. Cardiovascular effects of the 3 phosphodiesterase-5 inhibitors approved for the treatment of erectile dysfunction. Circulation 2004; 110(19): 3149-55.
Dumestre-Toulet V, Cirimele V, Gromb S, Belooussoff T, Lavault D, Ludes B, et al. Last performance with VIAGRA: Post-mortem identification of sildenafil and its metabolites in biological specimens including hair sample. Forensic Sci Int 2002; 126(1): 71-6.
Rasmussen JG, Toft E, Frobert O. Ventricular tachycardia after administration of sildenafil citrate: a case report. J Med Case Rep 2007; 1: 65.
Ilson BE, Shaddinger BC, Dabiri GA, Patel BR, Boyle DA, Sethuraman V, et al. A definitive study of the effects of PDE-5 inhibitors on cardiac repolarization in middle-age males. Clin Pharmacol Ther 2004; 75(2): 47.
Geelen P, Drolet B, Rail J, Berube J, Daleau P, Rousseau G, et al. Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. Circulation 2000; 102(3): 275-7.
Levine GN, Steinke EE, Bakaeen FG, Bozkurt B, Cheitlin MD, Conti JB, et al. Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2012; 125(8): 1058-72.
| Files | ||
| Issue | Vol 2 No 1 (2017): Winter | |
| Section | Case Report(s) | |
| Keywords | ||
| Sildenafil Ventricular arrhythmia Acute Myocardial infarction | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
