Typical Pulmonary Carcinoid Presenting with Massive Hemoptysis in Early Pregnancy: A Case Report
Abstract
Massive hemoptysis during pregnancy is a rare but potentially life-threatening emergency, and pulmonary carcinoid is an unusual underlying cause. We report a 31-year-old primigravida who presented at five weeks of gestation with sudden massive hemoptysis. Chest computed tomography and flexible bronchoscopy
revealed a hypervascular endobronchial lesion in the right bronchus intermedius causing partial airway obstruction and right middle lobe collapse. Histopathological and immunohistochemical examination confirmed a typical pulmonary carcinoid. Following multidisciplinary evaluation, definitive surgery was postponed until the
second trimester because the patient remained clinically stable without recurrent bleeding. At 12 weeks of gestation, she underwent right middle lobectomy with systematic mediastinal lymph node dissection, achieving complete (R0) resection with negative lymph nodes. The postoperative course was uneventful, and both maternal recovery and fetal development remained favorable during follow-up. This case highlights the importance of multidisciplinary management and appropriately timed surgical intervention in achieving favorable maternal, fetal, and oncologic outcomes.
org/10.1183/09031936.00085408
[2] Sakr L, Dutau H. Massive hemoptysis: an update on the role of bronchoscopy in diagnosis and management. Respiration. 2010;80(1):38-58. https://doi.org/10.1159/000274492
[3] Baudin E, Caplin M, Garcia-Carbonero R, et al. Lung and thymic carcinoids: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2021;32(4):439-451. https://doi.org/10.1016/j.annonc.2021.01.003
[4] Gosain R, Mukherjee S, Yendamuri SS, Iyer R. Management of Typical and Atypical Pulmonary Carcinoids Based on Different Established Guidelines. Cancers (Basel). 2018;10(12):510. https://doi.org/10.3390/cancers10120510
[5] WHO Classification of Tumours Editorial Board. Thoracic Tumours. WHO Classification of Tumours. 5th ed. Lyon:
International Agency for Research on Cancer; 2021.
[6] Nicholson AG, Tsao MS, Beasley MB, et al. The 2021 WHO Classification of Lung Tumors: Impact of Advances
Since 2015. J Thorac Oncol. 2022;17(3):362-387. https://doi.org/10.1016/j.jtho.2021.11.003
[7] Filosso PL, Guerrera F, Evangelista A, et al. Prognostic model of survival for typical bronchial carcinoid tumours:
analysis of 110 patients. Lung Cancer. 2015;90(1):24-29. https://doi.org/10.1016/j.lungcan.2015.07.011
[8] Reuling EMBP, Dickhoff C, Plaisier PW, et al. Surgery for pulmonary carcinoid tumors: long-term outcome and
prognostic factors. Eur J Cardiothorac Surg. 2019;56(4):646-652. https://doi.org/10.1093/ejcts/ezz113
[9] Hage R, de la Rivière AB, Seldenrijk CA, van den Bosch JMM. Update in pulmonary carcinoid tumors. Eur J Surg Oncol.
2003;29(5):461-474. https://doi.org/10.1053/ejso.2002.1409
[10] Thomas CF Jr, Tazelaar HD, Jett JR. Typical and atypical pulmonary carcinoids: outcome in patients presenting with
endobronchial disease. Chest. 2001;119(4):1143-1150. https://doi.org/10.1378/chest.119.4.1143
[11] Fink G, Krelbaum T, Yellin A, Bendayan D, Saute M, Glazer M, et al. Pulmonary carcinoid: presentation, diagnosis, and
outcome in 142 cases in Israel and review of 640 cases from the literature. Chest. 2001;119(6):1647-1651.
https://doi.org/10.1378/chest.119.6.1647
[12] Detterbeck FC. Management of carcinoid tumors. Ann Thorac Surg. 2010;89(3):998-1005. https://doi.org/10.1016/j.
athoracsur.2009.11.007
| Files | ||
| Issue | Vol 11 No 2 (2026): March-April | |
| Section | Case Report(s) | |
| Keywords | ||
| Pulmonary carcinoid Massive hemoptysis Pregnancy Lobectomy Multidisciplinary management. | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
