Limb Cutis Aplasia With Brain Thrombosis

Abstract

Cutis aplasia is a rare, benign, congenital, and localized skin defect disorder with multiple underlying causes. Vascular events are one of the underlying causes. However, they are not a common cause. Small cutis aplasia without bony defect gradually heals without any complication. Rare complications are seen in scalp aplasia with bony defect like hemorrhage, meningitis and thrombosis. We reported a neonate with limb skin aplasia of 4×3 cm size and normal other physical signs and symptoms. Gradually he developed overriding of skull sutures near his discharge time. We found a similar picture of the brain ischemia in imaging on the 24th day of his birth. This case and the similar cases may sugges an association between the vascular events and the cause of the disease. Thus, it is important to consider thrombosis and other vascular events in every patient with cutis aplasia even in a neonate with normal examination in the frs day. We recommend that physicians should not judge that the disease always has a good prognosis and follow up the patients’ condition anyway.