Hashimoto Encephalopathy with Sensory Polyneuropathy: A Case Report
Abstract
Hashimoto encephalopathy is an autoimmune disease characterized by an increase in antithyroid antibodies in the serum of patients with multiple neuropsychological symptoms. We report a case with lower level of antibody and fairly response to corticosteroid; however, clinical presentation, brain magnetic resonance imaging findings and the negative results of other diseases confirmed Hashimoto encephalopathy diagnosis. First, a relatively good corticosteroid response was seen but after one weak, the patient withdrew her drug and got back with a corticosteroid resistant progressive attack one month later. Our case had a mild increase in antithyroid antibodies and pure sensory polyneuropathy and did not show significant response to corticosteroid therapy. Can antithyroid antibodies titers be a marker of corticosteroid treatment response? this should be investigated in the future studies.
Schiess N, Pardo CA. Hashimoto's encephalopathy. Ann N Y Acad Sci 2008; 1142: 254-65.
Chen N, Qin W, Wei C, Wang X, Li K. Time course of Hashimoto's encephalopathy revealed by MRI: report of two cases. J Neurol Sci 2011; 300(1-2): 169-72.
Mijajlovic M, Mirkovic M, Dackovic J, Zidverc- Trajkovic J, Sternic N. Clinical manifestations, diagnostic criteria and therapy of Hashimoto's encephalopathy: report of two cases. J Neurol Sci 2010; 288(1-2): 194-6.
McGinley J, McCabe DJ, Fraser A, Casey E, Ryan T, Murphy R. Hashimoto's encephalopathy; an unusual cause of status epilepticus. Ir Med J 2000; 93(4): 118.
Bota VM, Corrigan DF. Hashimoto's encephalopathy in the setting of subclinical hypothyroidism. International Journal of Case Reports and Images 2011; 2(4): 19-22.
Pocsay G, Gazdag A, Engelhardt J, Szaniszlo I, Szolnoki Z, Forczek G, et al. Hashimoto encephalopathy. Orv Hetil 2013; 154(33): 1312-6. [In Hungarian].
Tamagno G, Celik Y, Simó R, Dihné M, Kimura K, Gelosa G, et al. Encephalopathy associated with autoimmune thyroid disease in patients with Graves' disease: clinical manifestations, follow-up, and outcomes. BMC Neurology 2010; 10: 27.
Wang J, Zhang J, Xu L, Shi Y, Wu X, Guo Q. Cognitive impairments in Hashimoto's encephalopathy: a case-control study. PLoS One 2013; 8(2): e55758.
Chong CS, Leung JL, Wong IH, Ng PW, Miao MY. Presenile dementia: a case of Hashimoto's encephalopathy. East Asian Arch Psychiatry 2011; 21(1): 32-6.
Chang JS, Chang TC. Hashimoto's encephalopathy: report of three cases. J Formos Med Assoc 2014; 113(11): 862-6.
Salpietro V, Granata V, Polizzi A, Mankad K, Briuglia S, Gallizzi R, et al. Hashimoto encephalopathy and peripheral neuropathy in an italian adolescent. The Child, a journal of pediatrics 2012; 1(2).
Sheng B, Lau KK, Li HL, Cheng LF. A case of Hashimoto's encephalopathy with demyelinating peripheral neuropathy. Eur Neurol 2005; 53(2): 84-5.
Toth CC. Severe sensory neuropathy occurring in association with Hashimoto's thyroid disease. J Peripher Nerv Syst 2005; 10(4): 394-5.
Cao NJ, Tselis AC, Li J, Gorman M. A case of Hashimoto's encephalopathy: association with sensory ganglionopathy. J Neurol Sci 2005; 238(1-2): 105-7.
Marshall GA, Doyle JJ. Long-term treatment of Hashimoto's encephalopathy. J Neuropsychiatry Clin Neurosci 2006; 18(1): 14-20.
Files | ||
Issue | Vol 1 No 1 (2016): Winter | |
Section | Case Report(s) | |
Keywords | ||
Antithyroid antibody Hashimoto encephalopathy Polyneuropathy |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |