Cryptococcal Lymphadenitis Without Meningitis in an HIV-Positive Patient: A Rare Case Report
Abstract
Cryptococcal infection is a chronic opportunistic infection in patients with the Human Immunodeficiency Virus (HIV). A rare case of cryptococcal lymphadenitis is presented here in a 27-year-old woman with an enlarged cervical lymph node. Fine needle aspiration from the involved lymph nodes showed variable-sized, rounded yeast cells surrounded by halos with a prominent capsule. Early diagnosis by fine-needle aspiration is essential and reduces morbidity and mortality.
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[9] Dharmshale SN, Patil SA, Gohil A, Chowdhary A, Oberoi C. Disseminated Crytococcosis with extensive cutaneous involvement in AIDS. Indian Journal of Medical Microbiology. 2006; 24(3):228-30. [PMID]
[10] Putignani L, Antonucci G, Paglia MG, Vincenzi L, Festa A, De Mori P, et al. Cryptococcal lymphadenitis as a manifestation of immune reconstitution inflammatory syndrome in an HIV-positive patient: A case report and review of the literature. International Journal of Immunopathology and Pharmacology. 2008; 21(3):751-6. [DOI:10. 1177/039463200802100332] [PMID]
[11] Katchanov J, Jefferys L, Tominski D, Wöstmann K, Slevogt H, Arastéh K, et al. Cryptococcosis in HIV-infected hospitalized patients in Germany: Evidence for routine antigen testing. The Journal of Infection. 2015; 71(1):110-6. [DOI:10.1016/j.jinf.2015.01.011] [PMID]
[12] Bao F, Tan H, Liu W, Li Y, Li H. Pediatric cryptococcal lymphadenitis in the absence of AIDS: Case report and literature review. Case Reports in Pediatrics. 2013; 2013:563081. [DOI:10.1155/2013/563081] [PMID] [PMCID]
[2] Deshmukh AT, Jagtap MW, Nafees N. Cytological evaluation of lymphadenopathy in HIV patients. International Journal of Recent Trends in Science and Technology. 2013; 6(3):125-9. https://www. medpulse.in/Pathology/Article/Volume1Issue1/Patho_1_1_4.pdf
[3] Andola KS, Ahuja M, Shaik I. Cryptococcal lymphadenitis on fine needle aspiration cytology: A report of 2 cases. People’s Journal of Scientific Research. 2012; 5(2):1-3. https://www.pjsr.org/July12_ pdf/8.%20Sainath%20Andola.pdf
[4] Srinivasan R, Gupta N, Shifa R, Malhotra P, Rajwanshi A, Chakrabarti A. Cryptococcal lymphadenitis diagnosed by fine needle aspiration cytology: A review of 15 cases. Acta Cytologica. 2010; 54(1):1-4. [DOI:10.1159/000324958] [PMID]
[5] Murakami Y, Oki M, Saka H, Kajikawa SH, Murakami A, Ishida A. Disseminated cryptococcosis presenting as mediastinal and hilar lymphadenopathy in an immunocompetent patient. Respirology Case Reports. 2016; 4(4):e00167. [DOI:10.1002/rcr2.167] [PMID] [PMCID]
[6] Qu J, Berbari E. Mediastinal Cryptococcoma in an immunocompetent host. Chest. 2017; 152(4):A141. [DOI:10.1016/j.chest.2017.08.172]
[7] Verma A, Sinha S, Verma AK. Cryptococcal lymphadenitis diagnosed on FNAC-primary manifestation in AIDS patient. International Journal of Medical Science and Public Health. 2016; 5(12):2641-2. [DOI:10.5455/ijmsph.2016.22062016534]
[8] Mitha M, Naicker P, Mahida P. Disseminated Cryptococcosis in an HIV-negative patient in South Africa: The elusive differential diagnosis. The Journal of Infection in Developing Countries. 2010; 4(8):526-9. [DOI:10.3855/jidc.813] [PMID]
[9] Dharmshale SN, Patil SA, Gohil A, Chowdhary A, Oberoi C. Disseminated Crytococcosis with extensive cutaneous involvement in AIDS. Indian Journal of Medical Microbiology. 2006; 24(3):228-30. [PMID]
[10] Putignani L, Antonucci G, Paglia MG, Vincenzi L, Festa A, De Mori P, et al. Cryptococcal lymphadenitis as a manifestation of immune reconstitution inflammatory syndrome in an HIV-positive patient: A case report and review of the literature. International Journal of Immunopathology and Pharmacology. 2008; 21(3):751-6. [DOI:10. 1177/039463200802100332] [PMID]
[11] Katchanov J, Jefferys L, Tominski D, Wöstmann K, Slevogt H, Arastéh K, et al. Cryptococcosis in HIV-infected hospitalized patients in Germany: Evidence for routine antigen testing. The Journal of Infection. 2015; 71(1):110-6. [DOI:10.1016/j.jinf.2015.01.011] [PMID]
[12] Bao F, Tan H, Liu W, Li Y, Li H. Pediatric cryptococcal lymphadenitis in the absence of AIDS: Case report and literature review. Case Reports in Pediatrics. 2013; 2013:563081. [DOI:10.1155/2013/563081] [PMID] [PMCID]
| Files | ||
| Issue | Vol 6 No 2 (2021): March-April | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/crcp.v6i2.6681 | |
| Keywords | ||
| Cryptococcus Meningitis Lymphadenopathy | ||
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How to Cite
1.
Atashabparvar A, Sajjadi H. Cryptococcal Lymphadenitis Without Meningitis in an HIV-Positive Patient: A Rare Case Report. CRCP. 2021;6(2):55-58.
