Retroperitoneal Angiomyolipoma in aWoman of Childbearing Age: A Case Report
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Abstract
Introduction: Extrarenal angiomyolipoma is an uncommon disease entity and is rare in the retroperitoneum. This lesion shows three benign components, including mature adipose tissue, thick-walled blood vessels, and smooth muscles.
Case Report: This report describes a 37-year-old woman who presented with incidental right retroperitoneal mass in prenatal checkup. The patient underwent excisional surgery. Histological examinations and the immunohistochemical study revealed angiomyolipoma. Based on the diagnosis, the patient received no more treatment. After 3 years of close follow- up examinations, no recurrence was observed.
Conclusion: This diagnosis is often confused with many other entities in retroperitoneum. Thus, imaging and histologic correlation are required. Proper diagnosis is essential for further patient management and avoids unnecessary treatment.
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[23] Halpenny D, Snow A, McNeill G, Torreggiani W. The radiologi- cal diagnosis and treatment of renal angiomyolipoma- Current status. Clinical Radiology. 2010; 65(2):99-108. [DOI:10.1016/j. crad.2009.09.014] [PMID]
[24] Jawahar A, Kazan-Tannus J. Retroperitoneal extrarenal angiomyoli- poma at the surgical bed 8 years after a renal angiomyolipoma ne- phrectomy: A case report and review of literature. Urology Annals. 2017; 9(3):288-92. [DOI:10.4103/UA.UA_20_17] [PMID] [PMCID]
[25] Eijkemans MJ, van der Wal W, Reijnders LJ, Roes KC, van Waalwijk van Doorn-Khosrovani SB, Pelletier C, et al. Long-term follow-up as- sessing renal angiomyolipoma treatment patterns, morbidity, and mortality: An observational study in tuberous sclerosis complex patients in the Netherlands. American Journal of Kidney Diseases. 2015; 66(4):638-45. [DOI:10.1053/j.ajkd.2015.05.016] [PMID]
[26] Kothary N, Soulen MC, Clark TWI, Wein AJ, Shlansky-Goldberg RD, Crino PB, et al. Renal angiomyolipoma: Long-term results after arterial embolization. Journal of Vascular and Interventional Radiology. 2005; 16(1):45-50. [DOI:10.1097/01.RVI.0000143769.79774.70] [PMID]
[2] L’Hostis H, Deminiere C, Ferriere JM, Coindre JM. Renal angiomy- olipoma: A clinicopathologic, immunohistochemical, and follow-up study of 46 cases. The American Journal of Surgical Pathology. 1999; 23(9):1011-20. [DOI:10.1097/00000478-199909000-00003] [PMID]
[3] Agaimy A, Vassos N, Croner RS, Strobel D, Lell M. Hepatic angiomy- olipoma: A series of six cases with emphasis on pathological-radio- logical correlations and unusual variants diagnosed by core needle biopsy. International Journal of Clinical and Experimental Pathology. 2012; 5(6):512-21. [PMID] [PMCID]
[4] Eble JN. Angiomyolipoma of kidney. Seminars in Diagnostic Pathol- ogy. 1998; 15(1):21-40. [PMID]
[5] Kim HJ, Chung CM, Park JY, Jung SG. Angiomyolipoma of the gla- bellar region. Archives of Craniofacial Surgery. 2017; 18(3):202-6. [DOI:10.7181/acfs.2017.18.3.202] [PMID] [PMCID]
[6] Tseng CA, Pan YS, Su YC, Wu DC, Jan CM, Wang WM. Extrarenal retroperitoneal angiomyolipoma: Case report and review of the literature. Abdominal Imaging. 2004; 29(6):721-3. [DOI:10.1007/ s00261-004-0179-2] [PMID]
[7] Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC, et al. Clinical correlates of renal angiomyolipoma subtypes in 209 pa- tients: Classic, fat poor, tuberous sclerosis associated and epithe- lioid. The Journal of Urology. 2008; 180(3):836-43. [DOI:10.1016/j. juro.2008.05.041] [PMID]
[8] Xu AM, Zhang SH, Zheng JM, Zheng WQ, Wu MC. Pathologi- cal and molecular analysis of sporadic hepatic angiomyolipoma. Human Pathology. 2006; 37(6):735-41. [DOI:10.1016/j.hump- ath.2006.01.028] [PMID]
[9] Stone CH, Lee MW, Amin MB, Yaziji H, Gown AM, Ro JY, et al. Re- nal angiomyolipoma: Further immunophenotypic characterization of an expanding morphologic spectrum. Archives of Pathology & Laboratory Medicine. 2001; 125(6):751-8. [DOI:10.5858/2001-125- 0751-RA] [PMID]
[10] Welling RD, Lungren MP, Coleman RE. Extrarenal retroperito- neal angiomyolipoma mimicking metastatic melanoma: CT and FDG PET correlation. Clinical Nuclear Medicine. 2012; 37(7):705-6. [DOI:10.1097/RLU.0b013e3182443c7d] [PMID]
[11] Ren N, Qin LX, Tang ZY, Wu ZQ, Fan J. Diagnosis and treatment of he- patic angiomyolipoma in 26 cases. World Journal of Gastroenterology. 2003; 9(8):1856-8. [DOI:10.3748/wjg.v9.i8.1856] [PMID] [PMCID]
[12] Fegan JE, Shah HR, Mukunyadzi P, Schutz MJ. Extrarenal retroperito- neal angiomyolipoma. Southern Medical Journal. 1997; 90(1):59-62. [DOI:10.1097/00007611-199701000-00013] [PMID]
[13] Dickinson M, Ruckle H, Beaghler M, Hadley H. Renal angiomy- olipoma: Optimal treatment based on size and symptoms. Clinical Nephrology. 1998; 49(5):281-6. [PMID]
[14] Prevoo W, van den Bosch MAAJ, Horenblas S. Radiofrequency ablation for treatment of sporadic angiomyolipoma. Urology. 2008; 72(1):188-91. [DOI:10.1016/j.urology.2008.02.059] [PMID]
[15] Faddegon S, So A. Treatment of angiomyolipoma at a tertiary care centre: The decision between surgery and angioembolization. Canadi- an Urological Association Journal. 2011; 5(6):E138-41. [PMID] [PMCID]
[16] Lee YC, Huang SP, Liu CC, Wu WJ, Chou YH, Huang CH. Giant ex- trarenal retroperitoneal angiomyolipoma: A case report and lit- erature review. The Kaohsiung Journal of Medical Sciences. 2003; 19(11):579-81. [DOI:10.1016/S1607-551X(09)70510-8] [PMID]
[17] Hruban RH, Bhagavan BS, Epstein JI. Massive retroperitoneal an- giomyolipoma. A lesion that may be confused with well-differen- tiated liposarcoma. American Journal of Clinical Pathology. 1989; 92(6):805-8. [DOI:10.1093/ajcp/92.6.805] [PMID]
[18] Nelson CP, Sanda MG. Contemporary diagnosis and management of renal angiomyolipoma. The Journal of Urology. 2002; 168(4 Pt 1):1315-25. [DOI:10.1016/S0022-5347(05)64440-0] [PMID]
[19] Zapardiel I, Delafuente-Valero J, Bajo-Arenas JM. Renal an- giomyolipoma during pregnancy: Review of the literature. Gynecologic and Obstetric Investigation. 2011; 72(4):217-9. [DOI:10.1159/000329328] [PMID]
[20] Kori C, Akhtar N, Vamsidhar PN, Gupta S, Kumar V. Giant exo- phytic renal angiomyolipoma mimicking as retroperitoneal sar- coma; A case report with review of literature. Journal of Clini- cal and Diagnostic Research. 2015; 9(4):XJ01-2. [DOI:10.7860/ JCDR/2015/11514.5798] [PMID] [PMCID]
[21] Vilcea ID, Victor R, Mirea CS, Simionescu CE, Mogoanta SS, Mora- ru E, et al. Extrarenal retroperitoneal angiomyolipoma with unusual evolution. Romanian Journal of Morphology and Embryology. 2015; 56(1):263-6. [PMID]
[22] Strahan A, King J, McClintock S. Retroperitoneal angiomyolipoma: A case report and review of the literature. Case Reports in Radiology. 2013; 2013:457383. [DOI:10.1155/2013/457383] [PMID] [PMCID]
[23] Halpenny D, Snow A, McNeill G, Torreggiani W. The radiologi- cal diagnosis and treatment of renal angiomyolipoma- Current status. Clinical Radiology. 2010; 65(2):99-108. [DOI:10.1016/j. crad.2009.09.014] [PMID]
[24] Jawahar A, Kazan-Tannus J. Retroperitoneal extrarenal angiomyoli- poma at the surgical bed 8 years after a renal angiomyolipoma ne- phrectomy: A case report and review of literature. Urology Annals. 2017; 9(3):288-92. [DOI:10.4103/UA.UA_20_17] [PMID] [PMCID]
[25] Eijkemans MJ, van der Wal W, Reijnders LJ, Roes KC, van Waalwijk van Doorn-Khosrovani SB, Pelletier C, et al. Long-term follow-up as- sessing renal angiomyolipoma treatment patterns, morbidity, and mortality: An observational study in tuberous sclerosis complex patients in the Netherlands. American Journal of Kidney Diseases. 2015; 66(4):638-45. [DOI:10.1053/j.ajkd.2015.05.016] [PMID]
[26] Kothary N, Soulen MC, Clark TWI, Wein AJ, Shlansky-Goldberg RD, Crino PB, et al. Renal angiomyolipoma: Long-term results after arterial embolization. Journal of Vascular and Interventional Radiology. 2005; 16(1):45-50. [DOI:10.1097/01.RVI.0000143769.79774.70] [PMID]
| Files | ||
| Issue | Vol 6 No 4 (2021): July-August | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/crcp.v6i4.7855 | |
| Keywords | ||
| Angiomyolipoma Retroperitoneum Pathology | ||
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How to Cite
1.
Moradi Tabriz H, nazar elham, Eftekhar Javadi A. Retroperitoneal Angiomyolipoma in aWoman of Childbearing Age: A Case Report. CRCP. 2021;6(4):150-154.
