Case Report

Unusual Abscess Caused by Brucella Melitensis


Brucellosis is a zoonotic infectious disease which any organ can be involved. Soft tissue lesions are rare manifestations of brucellosis. Brucella breast abscess in animal is not uncommon; involvement of the breast in human brucella is extremely rare. Breast abscess involvement was reported to 0.7% of the patient with brucellosis. We report the microbiological findings of breast abscess due to brucella. A 38-year-old woman living in the rural area of Kerman, Iran, presented with an abscess in the right breast. The sampling of the abscess aspiration and preparation of smears showed inflammatory fluid. Culture and PCR performed from the sample identified the presence of Brucella melitensis. The lesion had diminished in size after 8 weeks of treatment with combined doxycycline and rifampin. The possibility of breast abscess being caused by Brucella should be considered in countries, especially in endemic regions. Besides, isolated Brucella spp from microbiological cultures is important for a definitive diagnosis.

1. Shahabi Nejad N, Eftekhari N, Shahabi Nejad SH. A Case of Multi-Ulcerative Abscess Due to Brucella abortus in Kerman, South East of Iran. Iran J Med Sci. 2019,1-4. https://doi. org/10.30476/ijms.2018.40560
2. Tille PM. Brucella. Baily & scott’s Diagnostic Microbiology. 14th ed. Missouri USA: Elsevie.; 2017. p. 470-4.
3. Leong KN, Chow TS, Wong PS, Hamzah SH, Ahmad N, Ch’ng CC. Outbreak of Human Brucellosis from Consumption of Raw Goats’ Milk in Penang, Malaysia. Am J Trop Med Hyg. 2015; 93(5): 39-41. PubMed PMID: 26055742; PubMed Central PMCID: PMCPMC4559693. ajtmh.15-0246
4. Andriopoulos P, Tsironi M, Deftereos S, Aessopos A, Assimakopoulos G. Acute brucellosis: presentation, diagnosis, and treatment of 144 cases. Int J Infect Dis. 2007;11(1):52-7.
5. Besli Y, Karatuna O , Aksoy F, Akyar I. Isolation of Brucella melitensis from Breast Tissue: A Case Report. West Indian Med J.2016; 1-7.
6. Buzgan T, Karahocagil MK, Irmak H, Baran AI, Karsen H, Evirgen O, et al. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010; 14: 469–478. https://doi. org/10.1016/j.ijid.2009.06.031 PMID: 19910232
7. Abdely H. M. AI , Halim M. A , Amin T. M , Breast Abscess Caused by Brucella mefitensis, Journal of Infection. 1996; 33: 219-220. PMID: 8945713
8. Garshasbi M, Ramazani A, Sorouri R, Javani S, Moradi S, Molecular detection of Brucella species in patient suspicious of Brucellosis from Zanjan, Iran. Braz J Microbiol. 2014; 45(2):533- 538. PMCID: PMC4166279. PMID: 25242938
9. Ibrahim D, Dabbous H, Abi Aad, Y, Araj GF, Rizk NA. Simultaneous Brucella breast and pacemaker infection. IDCases. 2019; 15: e00485.
10. Sarrou S, Skoulakis C, Hajiioannou J, Petinaki E, Bizakis I. Brucella melitensis As Causative Agent for Neck Abscess in an Endemic Area. Balkan Med J. 2017; 34:78-80. balkanmedj.2015.1143. PubMed PMID: 28251029; PubMed Central PMCID: PMCPMC5322519.
IssueVol 7 No 6 (2022): November-December QRcode
SectionCase Report(s)
Brucellosis Brucella melitensis Breast abscess Polymerase chain reaction (PCR Endemic

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Eftekhari N, Mohammad Bagheri AH. Unusual Abscess Caused by Brucella Melitensis. CRCP. 2023;7(6):264-267.