High-Grade Endometrial Stromal Sarcoma with a Mucoid Grossly Feature: A Case Report of a 69-YearOld Iranian patient
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Abstract
Reporting clinical cases of high-grade endometrial stromal sarcoma tumors is essential for a better understanding of their natural course and for the development of appropriate diagnostic and treatment strategies. To date, only a few cases have been studied in this regard.In the present study, the authors present the case of a 69-year-old Iranian woman diagnosed with high-grade endometrial stromal sarcoma involving the myometrium and ovaries. The diagnosis was confirmed after pathology, which revealed myometrial and vascular involvement. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and adjuvant chemotherapy with chemotherapy regimens.
[1] Mbatani N, Olawaiye AB, Prat J. Uterine sarcomas. International Journal of Gynecology & Obstetrics. 2018;143:51-8. https:// doi.org/10.1002/ijgo.12613
[2] Seagle B-LL, Shilpi A, Buchanan S, Goodman C, Shahabi S. Low-grade and high-grade endometrial stromal sarcoma: a National Cancer Database study. Gynecologic oncology. 2017;146(2):254-62. https://doi.org/10.1016/j. ygyno.2017.05.036
[3] Hanby, A.M., walker, C. Tavassoli FA, Devilee P: Pathology and Genetics: Tumours of the Breast and Female Genital Organs. WHO Classification of Tumours series - volume IV. Lyon, France: IARC Press. Breast Cancer Res 6, 133 (2004). https:// doi.org/10.1186/bcr788
[4] Ali RH, Rouzbahman M. Endometrial stromal tumours revisited: an update based on the 2014 WHO classification. Journal of clinical pathology. 2015;68(5):325-32. https://doi. org/10.1136/jclinpath-2014-202829
[5] Kurman RJ, Carcangiu ML, Herrington CS, Young RH. WHO Classification of Tumours of Female Reproductive Organs. 4th ed. Lyon: International Agency for Research on Cancer; 2014.
[6] Bansal N, Herzog TJ, Burke W, Cohen CJ, Wright JD. The utility of preoperative endometrial sampling for the detection of uterine sarcomas. Gynecologic oncology. 2008;110(1):43-8. https://doi.org/10.1016/j.ygyno.2008.02.026
[7] Benjamins LJ. Practice guideline: evaluation and management of abnormal vaginal bleeding in adolescents. Journal of Pediat- ric Health Care. 2009;23(3):189-93. https://doi.org/10.1016/j. pedhc.2009.02.003
[8] Elmaoğulları S, Aycan Z. Abnormal uterine bleeding in adoles- cents. Journal of clinical research in pediatric endocrinology. 2018;10(3):191. https://doi.org/10.4274/jcrpe.0014
[9] Hanprasertpong J, Sakolprakraikij S, Geater A. Endometrial cancer in Thai women aged 45 years or younger. Asian Pac J Cancer Prev. 2008;9(1):58-62.
[10] Sachedina A, Chan K, MacGregor D, Campbell M, Grover SR. More than grapes and bleeding: an updated look at pelvic rhabdomyosarcoma in young women. Journal of Pediatric and Adolescent Gynecology. 2018;31(5):522-5. https://doi. org/10.1016/j.jpag.2018.01.006
[11] Jain R, Batra S, Ahmad A, Elahi AA, Gupta M, Saith P. Low grade endometrial stromal sarcoma: a case report. Iranian journal of medical sciences. 2015;40(1):81-4.
[12] Puliyath G, Nair MK. Endometrial stromal sarcoma: A review of the literature. Indian J Med Paediatr Oncol. 2012;33(01):1- 6. https://doi.org/10.4103/0971-5851.96960
[13] Aubry M-C, Myers JL, Colby TV, Leslie KO, Tazelaar HD. Endometrial stromal sarcoma metastatic to the lung: a detailed analysis of 16 patients. The American journal of surgical pathology. 2002;26(4):440-9. https://doi. org/10.1097/00000478-200204000-00005
[14] Matsuura Y, Yasunaga K, Kuroki H, Inagaki H, Kashimura M. Low- grade endometrial stromal sarcoma recurring with multiple bone and lung metastases: report of a case. Gynecologic oncology. 2004;92(3):995-8. https://doi.org/10.1016/j.ygyno.2003.11.047
[15] Gadducci A, Cosio S, Romanini A, Genazzani AR. The management of patients with uterine sarcoma: a debated clinical challenge. Critical reviews in oncology/ hematology. 2008;65(2):129-42. https://doi.org/10.1016/j. critrevonc.2007.06.011
[2] Seagle B-LL, Shilpi A, Buchanan S, Goodman C, Shahabi S. Low-grade and high-grade endometrial stromal sarcoma: a National Cancer Database study. Gynecologic oncology. 2017;146(2):254-62. https://doi.org/10.1016/j. ygyno.2017.05.036
[3] Hanby, A.M., walker, C. Tavassoli FA, Devilee P: Pathology and Genetics: Tumours of the Breast and Female Genital Organs. WHO Classification of Tumours series - volume IV. Lyon, France: IARC Press. Breast Cancer Res 6, 133 (2004). https:// doi.org/10.1186/bcr788
[4] Ali RH, Rouzbahman M. Endometrial stromal tumours revisited: an update based on the 2014 WHO classification. Journal of clinical pathology. 2015;68(5):325-32. https://doi. org/10.1136/jclinpath-2014-202829
[5] Kurman RJ, Carcangiu ML, Herrington CS, Young RH. WHO Classification of Tumours of Female Reproductive Organs. 4th ed. Lyon: International Agency for Research on Cancer; 2014.
[6] Bansal N, Herzog TJ, Burke W, Cohen CJ, Wright JD. The utility of preoperative endometrial sampling for the detection of uterine sarcomas. Gynecologic oncology. 2008;110(1):43-8. https://doi.org/10.1016/j.ygyno.2008.02.026
[7] Benjamins LJ. Practice guideline: evaluation and management of abnormal vaginal bleeding in adolescents. Journal of Pediat- ric Health Care. 2009;23(3):189-93. https://doi.org/10.1016/j. pedhc.2009.02.003
[8] Elmaoğulları S, Aycan Z. Abnormal uterine bleeding in adoles- cents. Journal of clinical research in pediatric endocrinology. 2018;10(3):191. https://doi.org/10.4274/jcrpe.0014
[9] Hanprasertpong J, Sakolprakraikij S, Geater A. Endometrial cancer in Thai women aged 45 years or younger. Asian Pac J Cancer Prev. 2008;9(1):58-62.
[10] Sachedina A, Chan K, MacGregor D, Campbell M, Grover SR. More than grapes and bleeding: an updated look at pelvic rhabdomyosarcoma in young women. Journal of Pediatric and Adolescent Gynecology. 2018;31(5):522-5. https://doi. org/10.1016/j.jpag.2018.01.006
[11] Jain R, Batra S, Ahmad A, Elahi AA, Gupta M, Saith P. Low grade endometrial stromal sarcoma: a case report. Iranian journal of medical sciences. 2015;40(1):81-4.
[12] Puliyath G, Nair MK. Endometrial stromal sarcoma: A review of the literature. Indian J Med Paediatr Oncol. 2012;33(01):1- 6. https://doi.org/10.4103/0971-5851.96960
[13] Aubry M-C, Myers JL, Colby TV, Leslie KO, Tazelaar HD. Endometrial stromal sarcoma metastatic to the lung: a detailed analysis of 16 patients. The American journal of surgical pathology. 2002;26(4):440-9. https://doi. org/10.1097/00000478-200204000-00005
[14] Matsuura Y, Yasunaga K, Kuroki H, Inagaki H, Kashimura M. Low- grade endometrial stromal sarcoma recurring with multiple bone and lung metastases: report of a case. Gynecologic oncology. 2004;92(3):995-8. https://doi.org/10.1016/j.ygyno.2003.11.047
[15] Gadducci A, Cosio S, Romanini A, Genazzani AR. The management of patients with uterine sarcoma: a debated clinical challenge. Critical reviews in oncology/ hematology. 2008;65(2):129-42. https://doi.org/10.1016/j. critrevonc.2007.06.011
| Files | ||
| Issue | Vol 8 No 5 (2023): September-October | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/crcp.v8i5.15261 | |
| Keywords | ||
| Sarcoma Endometrium Endometrial stromal sarcoma Cervix Ovary Hysterectomy Abdomen Uterine bleeding | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Mahdizadeh F, Chinifroush-Asl MM, Heidary F, Hataminia H. High-Grade Endometrial Stromal Sarcoma with a Mucoid Grossly Feature: A Case Report of a 69-YearOld Iranian patient. CRCP. 2024;8(5):208-211.
