Case Report

A Colorectal Adenocarcinoma With Obstruction in a 26-Year-Old Man: A Case Report in an Unlikely Age Group

Abstract

Colorectal cancer affects the rectum or large bowel, including the appendix. This type of cancer develops from the colorectal mucosa, with adenocarcinoma being the most common form, accounting for over 95% of cases. It typically affects individuals aged 50 years or older. However, this report highlights a case of colorectal adenocarcinoma that occurred at a young age, despite no family history. Unfortunately, the cancer was initially missed during check-ups because of the unlikely age group, resulting in a delayed diagnosis. The patient, who presented with an obstruction, underwent surgical interventions. Upon further examination, the histopathological tests revealed that the patient had well-differentiated type I colorectal adenocarcinoma.

[1]Thrumurthy SG, Thrumurthy SS, Gilbert CE, Ross P, Haji A. Colorectal adenocarcinoma: risks, prevention and diagnosis.
BMJ. 2016;354. https://doi.org/10.1136/bmj.i3590
[2] Schumacher AJ, Chen Q, Attaluri V, McLemore EC, Chao CR. Metabolic risk factors associated with early-onset colorectal adenocarcinoma: a case-control study at Kaiser Permanente Southern California. Cancer Epidemiol Biomarkers Prev. 2021;30(10):1792-8. https://doi.org/10.1158/1055-9965.EPI- 20-1127
[3] Mattiuzzi C, Sanchis-Gomar F, Lippi G. Concise update on colorectal cancer epidemiology. Ann Transl Med. 2019;7(21). https://doi.org/10.21037/atm.2019.07.91
[4] Ahmed SZ, Cirocchi N, Saxton E, Brown MK. Incidence of age migration of colorectal cancer in younger population: Retrospective single centred-population based cohort study. Ann Med Surg (Lond). 2022;74:103214. https://doi. org/10.1016/j.amsu.2021.103214
[5] Mitry E, Benhamiche A-M, Jouve J-L, Clinard F, Finn-Faivre C, Faivre J. Colorectal adenocarcinoma in patients under 45 years of age: comparison with older patients in a well-defined French population. Dis Colon Rectum. 2001;44:380-7. https://doi. org/10.1007/BF02234737
[6] Chang DT, Pai RK, Rybicki LA, Dimaio MA, Limaye M, Jayachandran P, et al. Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features. Mod Pathol. 2012;25(8):1128-39. https://doi. org/10.1038/modpathol.2012.61
[7] Chen H-S, Sheen-Chen S-M. Obstruction and perforation in colorectal adenocarcinoma: an analysis of prognosis and current trends. Surgery. 2000;127(4):370-6. https://doi. org/10.1067/msy.2000.104674
[8]Wilkinson N, Scott-Conner CE. Surgical therapy for colorectal adenocarcinoma. Gastroenterol Clin North Am. 2008;37(1):253- 67. https://doi.org/10.1016/j.gtc.2007.12.012
Files
IssueVol 8 No 4 (2023): July-August QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/crcp.v8i4.14576
Keywords
Colorectal cancer Adenocarcinoma Colon Rectosigmoid
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Mahdizadeh F, Chinifroush-Asl MM, Heidary F. A Colorectal Adenocarcinoma With Obstruction in a 26-Year-Old Man: A Case Report in an Unlikely Age Group. CRCP. 2024;8(4):159-162.