Case Report

Pyoderma Gangrenosum-like Ulcers Associated Granulomatosis with Polyangiitis

Abstract

Granulomatosis with polyangiitis is an ANCA-positive vasculitis primarily affecting small to medium-sized vessels, typically involving the lungs and kidneys. This article presents a remarkable case of a patient with an unusual pyoderma gangrenosum-like ulcer on the face and granulomatosis with polyangiitis.  A 28-year-old man, previously diagnosed with granulomatosis with polyangiitis presented at a dermatology clinic with a 6-month-old ulcer in the right preauricular region following a traumatic incident. A spindle biopsy revealed suppurative granulomatous dermatitis with secondary vascular damage, while cultures showed no signs of infection. The patient was subsequently treated with rituximab, leading to a positive clinical response. This case underscores the challenge of diagnosing this rare manifestation of granulomatosis with polyangiitis and suggests that rituximab could be a valuable treatment option.

 

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IssueVol 9 No 1 (2024): January-February QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/crcp.v9i1.16822
Keywords
Granulomatosis Polyangiitis Pyoderma Gangrenosum Rituximab Vasculitis
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How to Cite
1.
Avila K, López López K, Durand Muñoz M, Domínguez Cherit J. Pyoderma Gangrenosum-like Ulcers Associated Granulomatosis with Polyangiitis. CRCP. 2024;9(1):6-9.