Case Report

Kawasaki Disease in an Adult Woman from Iran


Kawasaki disease is a rheumatologic disorder that is due to small- to medium-sized vessels necrotizing vasculitis with unknown origin. The disease affects children predominantly, but rarely occurs in adults. We report a case of 23-year-old woman from Iran who had got high grade fever, bilateral non-purulent conjunctivitis, myalgia, palms and soles exanthema, and desquamation. After 5 days of empirical antibiotic therapy without any organisms identified for source of infection, the diagnosis was established. No treatment with intravenous gammaglobulin and aspirin was administered and her echocardiogram showed normal coronary arteries. The age of our patient is an unusual aspect of the disease presentation in Iran. The diagnosis of Kawasaki in adults should be considered in patients with prolonged fever not responding to antibiotics with clinical features of Kawasaki disease.

Fraison JB, Seve P, Dauphin C, Mahr A, Gomard-Mennesson E, Varron L, et al. Kawasaki disease in adults: Observations in France and literature review. Autoimmun Rev 2016; 15(3): 242-9.

Kontopoulou T, Kontopoulos DG, Vaidakis E, Mousoulis GP. Adult Kawasaki disease in a European patient: A case report and review of the literature. J Med Case Rep 2015; 9: 75.

Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: A statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics 2004; 114(6): 1708-33.

Drago F, Javor S, Ciccarese G, Cozzani E, Parodi A. A case of complete adult-onset Kawasaki disease: A review of pathogenesis and classification. Dermatology 2015; 231(1): 5-8.

Gomard-Mennesson E, Landron C, Dauphin C, Epaulard O, Petit C, Green L, et al. Kawasaki disease in adults: Report of 10 cases. Medicine (Baltimore) 2010; 89(3): 149-58.

Stankovic K, Miailhes P, Bessis D, Ferry T, Broussolle C, Seve P. Kawasaki-like syndromes in HIV-infected adults. J Infect 2007; 55(6): 488-94.

Garrido-Garcia LM, Lopez-Amezquita M, Villaverde-Rosas R. Kawasaki disease in a healthcare provider: An adult case in a paediatric resident. Cardiol Young 2016; 26(5): 976-8.

IssueVol 2 No 3 (2017): Summer QRcode
SectionCase Report(s)
Kawasaki disease Vasculitis Rheumatic diseases

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Rezaei Jouzdani S, Pakzad B. Kawasaki Disease in an Adult Woman from Iran. CRCP. 2018;2(3):67-70.