Esophageal Squamous Cell Carcinoma Presenting as Two Simultaneous Adjacent Masses Confirmed by Pathologic Findings: Report of a Rare Case
Abstract
Esophageal squamous cell carcinoma (SCC) is a common neoplasm which incidence shows an increasing trend in most populations. This article presents a case of 79-year-old woman with diagnosis of differentiated squamous cell carcinoma of the esophagus as two adjacent mas with metastasis, which invaded the perigastric and distal esophagus lymph nodes. The patient underwent esophagectomy and gastroesophagotomy. The jejunostomy tube was also embedded. The presence of two simultaneous esophageal tumoral lesions is extremely uncommon and requires further assessments. The prognosis and survival of such patients not seems to be worse than those of patients with isolated esophageal neoplasm.
Napier KJ, Scheerer M, Misra S. Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment
modalities. World J Gastrointest Oncol 2014; 6(5): 112-20.
Zhang Y. Epidemiology of esophageal cancer. World J Gastroenterol 2013; 19(34): 5598-606.
Pennathur A, Gibson MK, Jobe BA, Luketich JD. Oesophageal carcinoma. Lancet 2013; 381(9864): 400-12.
Alema ON, Iva B. Cancer of the esophagus: Histopathological sub-types in northern Uganda. Afr Health Sci 2014; 14(1): 17-21.
Zhang HZ, Jin GF, Shen HB. Epidemiologic differences in esophageal cancer between Asian and Western populations. Chin J Cancer 2012; 31(6): 281-6.
Tran GD, Sun XD, Abnet CC, Fan JH, Dawsey SM, Dong ZW, et al. Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China. Int J Cancer 2005; 113(3): 456-63.
Domper Arnal MJ, Ferrandez Arenas A, Lanas Arbeloa A. Esophageal cancer: risk factors, screening and endoscopic treatment in western and eastern countries. World J Gastroenterol 2015; 21(26): 7933-43.
de Villiers EM, Gunst K, Stein H, Scherubl H. Esophageal squamous cell cancer in patients with head and neck cancer: Prevalence of human papillomavirus DNA sequences. Int J Cancer 2004; 109(2): 253-8.
Kim JS, Kim BW. Esophageal cancer and head and neck cancer: The earlier, the better. Gut Liver 2015; 9(2): 131-2.
Lambert R, Hainaut P. The multidisciplinary management of gastrointestinal cancer. Epidemiology of oesophagogastric cancer.
Best Pract Res Clin Gastroenterol 2007; 21(6): 921-45.
Brown LM. The role of race/ethnicity in the epidemiology of esophageal cancer. J Assoc Acad Minor Phys 2000; 11(2-3): 32-7.
Melhado RE, Alderson D, Tucker O. The changing face of esophageal cancer. Cancers (Basel) 2010; 2(3): 1379-404.
Huang FL, Yu SJ. Esophageal cancer: Risk factors, genetic association, and treatment. Asian J Surg 2018; 41(3): 210-5.
Jian X, Lianshang W, Fauli M. Missed Diagnosis and Prevention of Multicentric Tumors of Upper Alimentary Tract-Report of 28 Patients. Chinese Journal of Clinkal Oncology and Rehabilitation 1998; 2: 025.
Sun X, Zou Y, Hao Y, Cheng H, Zhou C, Meng X. Pathological analysis of collision (double primary) cancer in the upper digestive tract concomitant with gastric stromal tumor: A case report. Int J Clin Exp Pathol 2015; 8(10): 13523-7.
Schizas D, Michalinos A, Alexandrou P, Moris D, Baliou E, Tsilimigras D, et al. A unique tripartite collision tumor of the esophagus: A case report. Medicine (Baltimore) 2017; 96(49): e8784.
Zhang HD, Chen CG, Gao YY, Ma Z, Tang P, Duan XF, et al. Primary esophageal adenosquamous carcinoma: A retrospective analysis of 24 cases. Dis Esophagus 2014; 27(8): 783-9.
Huguenin JF, Azevedo VV, Almeida HI, Oliveira IM, Pinto CE. Synchronous esophageal squamous cell carcinoma and gastric adenocarcinoma. Arq Bras Cir Dig 2013; 26(3): 246-7.
Maleki I, Shekarriz R, Nosrati A, Orang E. simultaneous esophageal squamous cell carcinoma and adenocarcinoma: A case report. Middle East J Dig Dis 2015; 7(4): 257-60.
Li X, Lin S, Zhang Y, Wang H. Synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma: Analysis of 41 cases treated in a single institution. Sci Rep
; 5: 13335.
Han JS, Choi SR, Jang JS, Roh MH, Kim DC, Ryu SH, et al. A Case of synchronous esophagus and stomach cancer successfully treated by combined chemotherapy. Korean J Gastroenterol 2012; 60(2): 113-8.
Files | ||
Issue | Vol 3 No 1 (2018): Winter | |
Section | Case Report(s) | |
Keywords | ||
Esophageal neoplasms Squamous cell carcinoma Pathology |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |