Subependymal Heterotopia With Psychosis and Imperforate Anus in a Female Patent
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Abstract
In the last couple of years, with the advancement of imaging methods, the diagnosis of gray matter heterotopia has been more promising. Gray matter heterotopia is a rare disorder in the general population, but recent attention to its psychiatric aspects encouraged us to introduce a patient with a form of gray matter heterotopia, who suffers from the anatomical abnormalities with a variety of psychiatric disorders. Our patient is a 25-year-old woman, who presented a variety of organogenesis disorders such as imperforate anus and rectovaginal fistula with the presence of gray matter heterotopia and history of refractory mood and psychotic disorders during 9 past years. Because of the various clinical manifestations of the disease, syndromic attention to this disease seems to be helpful in diagnosing and treating its various aspects.
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[PMID]
[9] Gomez-Garre P, Seijo M, Guterrez-Delicado E, Del Río MC, de la Torre C, Gomez-Abad C, et al. Ehlers-Danlos syndrome and periventricular nodular heterotopia in a Spanish family with a single FLNA mutaton. Journal of Medical Genetcs. 2006; 43(3):232-7. [DOI:10.1136/jmg.2004.029173] [PMID] [PMCID]
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[13] Cho WH, Seidenwurm D, Barkovich AJ. Adult-onset neurologic dysfuncton associated with cortcal malformatons. American Journal of Neuroradiology. 1999; 20(6):1037-43. [PMID]
[14] Nopoulos P, Swayze V, Flaum M, Andreasen NC. Incidence of ectopic gray mater in patents with schizophrenia and healthy control subjects studied with MRI. The Journal of Neuropsychiatry and Clinical Neurosciences. 1998; 10(3):351-3. [DOI:10.1176/jnp.10.3.351] [PMID]
[15] Statovci S, Heta H, Hyseni N, Grajçevci S, Berisha M, Çeku G. Treatment of children with anorectal malformatons-10 year review. Open Access Library Journal. 2015; 2:e1393. [DOI:10.4236/ oalib.1101393]
[2] Lippi G. Neuropsychiatric symptoms and diagnosis of grey mater heterotopia: A case-based reflecton. South African Journal of Psychiatry. 2017; 23(1):1-6. [DOI:10.4102/sajpsychiatry.v23i0.923]
[3] Zannolli R, Conversano E, Serracca L, Di Bartolo R, Molinelli M, Galluzzi P, et al. Cortcal periventricular heterotopia with ectodermal dysplasia. American Journal of Medical Genetcs Part A. 2002; 113(4):385-9. [DOI:10.1002/ajmg.b.10811] [PMID]
[4] Raymond A, Fish D, Sisodiya S, Alsanjari N, Stevens J, Shorvon S. Abnormalites of gyraton, heterotopias, tuberous sclerosis, focal cortcal dysplasia, microdysgenesis, dysembryoplastc neuroepithelial tumour and dysgenesis of the archicortex in epilepsy: Clinical, EEG and neuroimaging features in 100 adult patents. Brain. 1995; 118(3):629-60. [DOI:10.1093/brain/118.3.629] [PMID]
[5] Fry AE, Kerr MP, Gibbon F, Turnpenny PD, Hamandi K, Stoodley N, et al. Neuropsychiatric disease in patents with periventricular heterotopia. The Journal of Neuropsychiatry and Clinical Neurosciences. 2013; 25(1):26-31. [DOI:10.1176/appi.neuropsych.11110336] [PMID]
[6] Barkovich AJ, Kuzniecky RI. Gray mater heterotopia. Neurology. 2000; 55(11):1603-8. [DOI:10.1212/WNL.55.11.1603]
[7] Meroni A, Galli C, Bramerio M, Tassi L, Colombo N, Cossu M, et al. Nodular heterotopia: A neuropathological study of 24 patents undergoing surgery for drug-resistant epilepsy. Epilepsia. 2009; 50(1):116-24. [DOI:10.1111/j.1528-1167.2008.01717.x] [PMID]
[8] Nagaraj U, Peiro J, Bierbrauer K, Kline-Fath B. Evaluaton of subependymal gray mater heterotopias on fetal MRI. American Journal of Neuroradiology. 2016; 37(4):720-5. [DOI:10.3174/ajnr.A4585]
[PMID]
[9] Gomez-Garre P, Seijo M, Guterrez-Delicado E, Del Río MC, de la Torre C, Gomez-Abad C, et al. Ehlers-Danlos syndrome and periventricular nodular heterotopia in a Spanish family with a single FLNA mutaton. Journal of Medical Genetcs. 2006; 43(3):232-7. [DOI:10.1136/jmg.2004.029173] [PMID] [PMCID]
[10] Acar G, Acar F, Öztura İ, Baklan B. A case report of surgically treated drug resistant epilepsy associated with subependymal nodular heterotopia. Seizure-European Journal of Epilepsy. 2012; 21(3):223- 6. [DOI:10.1016/j.seizure.2011.11.002] [PMID]
[11] Pridmore S, McInerney G, Rybak M, Archer S. Psychotc disorder NOS with heterotopia. Journal of Psychiatric Intensive Care. 2006; 2(2):118-21. [DOI:10.1017/S1742646407000386]
[12] Christodoulou JA, Walker LM, Del Tufo SN, Katzir T, Gabrieli JD, Whitield-Gabrieli S, et al. Abnormal structural and functonal brain connectvity in gray mater heterotopia. Epilepsia. 2012; 53(6):1024- 32. [DOI:10.1111/j.1528-1167.2012.03466.x] [PMID] [PMCID]
[13] Cho WH, Seidenwurm D, Barkovich AJ. Adult-onset neurologic dysfuncton associated with cortcal malformatons. American Journal of Neuroradiology. 1999; 20(6):1037-43. [PMID]
[14] Nopoulos P, Swayze V, Flaum M, Andreasen NC. Incidence of ectopic gray mater in patents with schizophrenia and healthy control subjects studied with MRI. The Journal of Neuropsychiatry and Clinical Neurosciences. 1998; 10(3):351-3. [DOI:10.1176/jnp.10.3.351] [PMID]
[15] Statovci S, Heta H, Hyseni N, Grajçevci S, Berisha M, Çeku G. Treatment of children with anorectal malformatons-10 year review. Open Access Library Journal. 2015; 2:e1393. [DOI:10.4236/ oalib.1101393]
| Files | ||
| Issue | Vol 3 No 4 (2018): Autumn | |
| Section | Case Report(s) | |
| Keywords | ||
| Imperforate anus Psychosis Subependymal heterotopia | ||
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How to Cite
1.
Badrfam R, Zandifar A, Ahmadi Abhari SA. Subependymal Heterotopia With Psychosis and Imperforate Anus in a Female Patent. CRCP. 2019;3(4):113-117.
