Cutaneous Metastasis of Chondrosarcoma: A Case Report With Literature Review
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Abstract
The metastasis to respiratory system secondary to chondrosarcoma is a common finding; however, metastasis to other organs such as skin or bones is much less common. In the current report, we described a case with the history of chondrosarcoma of the mandible that recently referred with the metastatic lesions in her scalp skin. Our case is a female patient that its secondary metastasis occurred only 4 months after her initial tumor diagnosis. More interestingly, among all baseline laboratory parameters, only inflammatory biomarkers increased as the nonspecific diagnostic indices. In other words, the accurate diagnosis of metastasis to bone following chondrosarcoma may be delayed and even masked with early inflammatory reactions. On the whole, in all patients who suffer from chondrosarcoma, early metastasis to skin or bones should be considered, especially when inflammatory indices are high.
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[12] Sherr DL, Fountain KS, Kalb RE. Cutaneous metastases from chondrosarcoma. Journal of Dermatologic Surgery and Oncology. 1986; 12(2):146-9. [DOI:10.1111/j.1524-4725.1986.tb01445.x] [PMID]
[13] Karabela-Bouropoulou V, Patra-Malli F, Agnants N. Chondrosarcoma of the thumb: An unusual case with lung and cutaneous metastases and death of the patent 6 years afer treatment. Journal of Cancer Research and Clinical Oncology. 1986; 112(1):71-4. [DOI:10.1007/BF00394943]
[14] Amadio PC, Lombardi RM. Metastatc tumors of the hand. Journal of Hand Surgery 1987; 12(2):311-6. [DOI:10.1016/S0363- 5023(87)80299-X] [PMID]
[15] Bashi VV, Walter A, John S. Primary chondrosarcoma of heart. Indian Journal of Chest Diseases & Allied Sciences. 1989; 31(3):203-6. [PMID]
[16] Leal-Khouri SM, Barnhill RL, Baden HP. An unusual cutaneous metastasis of a chondrosarcoma. Journal of Cutaneous Pathology. 1990; 17(5):274-7. [DOI:10.1111/j.1600-0560.1990.tb00102.x] [PMID]
[17] Lambert D, Escallier F, Collet E, Dallac S, Maingon P, Mayer F, et al. Distal phalangeal metastasis of a chondrosarcoma presentng initally as bilateral onycholysis. Journal of Clinical & Experimental Dermatology Research. 1992; 17:463-5. [DOI:10.1111/j.1365-2230.1992. tb00263.x] [PMID]
[18] Damron TA, Rock MG, Unni KK. Subcutaneous involvement afer a metacarpal chondrosarcoma. case report and review of literature. Clinical Orthopaedics and Related Research. 1995; 316:189-94. [DOI:10.1097/00003086-199507000-00026] [PMID]
[2] Kim HS, Bindiganavile SS, Han I. Oncologic outcome afer local recurrence of chondrosarcoma: Analysis of prognostc factors. Journal of Surgical Oncology. 2015; 111(8):957-61. [DOI:10.1002/ jso.23925] [PMID]
[3] Leddy LR, Holmes RE. Chondrosarcoma of bone. Cancer Treatment and Research. 2014; 162:117-30. [DOI:10.1007/978-3-319-07323- 1_6] [PMID]
[4] Czerniak B. Dorfman and czerniak’s bone tumors. St Louis: Mosby; 1998.
[5] Ragsdale MI, Lehmer LM, Ragsdale BD, Chow WA, Carson RT. Cutaneous metastasis of osteosarcoma in the scalp. The American Journal of Dermatopathology. 2011; 33(6):e70-3. [DOI:10.1097/ DAD.0b013e318214a7ea] [PMID]
[6] Shah ND, Diwanji SR. Primary chondrosarcoma of the lung with cutaneous and skeletal metastases. Singapore Medical Journal. 2007; 48(7):e196-9. [PMID]
[7] Malek B, Thomas M, Nilles M, Schill WB. Solitary subcutaneous metastasis of a chondrosarcoma. Hautarzt. 1994; 45(10):722-4. [DOI:10.1007/s001050050158] [PMID]
[8] Cruickshank AH. Chondrosarcoma of a phalanx with cutaneous metastasis. Journal Pathology Bacteriology 1945; 57(1):144-45. [DOI:10.1002/path.1700570118]
[9] Froimson A. Metastatc chondrosarcoma of the hand. report of a case. Clinical Orthopedic Relatons Research 1967; 53:155-160. [DOI:10.1097/00003086-196707000-00018] [PMID]
[10] King DT, Gurevitch AW, Hirose FM. Multple cutaneous metastases of a scapular chondrosarcoma. Archives of Dermatology. 1978; 114(4):584-6. [DOI:10.1001/archderm.1978.01640160062018] [PMID]
[11] Kerin R. Metastatc tumors of the hand: A review of the literature. The Journal of Bone and Joint Surgery American Volume. 1983; 65(9)1331-5. [DOI:10.2106/00004623-198365090-00016] [PMID]
[12] Sherr DL, Fountain KS, Kalb RE. Cutaneous metastases from chondrosarcoma. Journal of Dermatologic Surgery and Oncology. 1986; 12(2):146-9. [DOI:10.1111/j.1524-4725.1986.tb01445.x] [PMID]
[13] Karabela-Bouropoulou V, Patra-Malli F, Agnants N. Chondrosarcoma of the thumb: An unusual case with lung and cutaneous metastases and death of the patent 6 years afer treatment. Journal of Cancer Research and Clinical Oncology. 1986; 112(1):71-4. [DOI:10.1007/BF00394943]
[14] Amadio PC, Lombardi RM. Metastatc tumors of the hand. Journal of Hand Surgery 1987; 12(2):311-6. [DOI:10.1016/S0363- 5023(87)80299-X] [PMID]
[15] Bashi VV, Walter A, John S. Primary chondrosarcoma of heart. Indian Journal of Chest Diseases & Allied Sciences. 1989; 31(3):203-6. [PMID]
[16] Leal-Khouri SM, Barnhill RL, Baden HP. An unusual cutaneous metastasis of a chondrosarcoma. Journal of Cutaneous Pathology. 1990; 17(5):274-7. [DOI:10.1111/j.1600-0560.1990.tb00102.x] [PMID]
[17] Lambert D, Escallier F, Collet E, Dallac S, Maingon P, Mayer F, et al. Distal phalangeal metastasis of a chondrosarcoma presentng initally as bilateral onycholysis. Journal of Clinical & Experimental Dermatology Research. 1992; 17:463-5. [DOI:10.1111/j.1365-2230.1992. tb00263.x] [PMID]
[18] Damron TA, Rock MG, Unni KK. Subcutaneous involvement afer a metacarpal chondrosarcoma. case report and review of literature. Clinical Orthopaedics and Related Research. 1995; 316:189-94. [DOI:10.1097/00003086-199507000-00026] [PMID]
| Files | ||
| Issue | Vol 4 No 3 (2019): Summer | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/crcp.v4i3.1712 | |
| Keywords | ||
| Chondrosarcoma; Metastasis; Skin; Survival | ||
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How to Cite
1.
Nazar E, Ghanadan A. Cutaneous Metastasis of Chondrosarcoma: A Case Report With Literature Review. CRCP. 2019;4(3):73-77.
