Posterior Cortical Atrophy With Interesting Presentation: Case Reports
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Abstract
Posterior Cortical Atrophy (PCA) is a rare neuropsychiatric syndrome characterized by the dominancy of visuospatial impairments due to bilateral parieto-occipital divesting with the most common pathological changes presented in typical Alzheimer’s Disease (AD). We reported 3 cases with similar diagnoses and interesting manifestations in this study. Gradual onset and progression of visual deficits without underlying ophthalmologic disease accompanied by intact memory and fluent speech and also the presence of simultagnosia, optic ataxia, oculomotor apraxia, dyscalculia, finger agnosia, and environmental disorientation, and the absence of any history of related diseases; all of them strongly suggesting posterior cortical atrophy.
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[8] Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Tang-Wai DF, Dru- bach DA, et al. Visual hallucinations in posterior cortical atrophy. Archives of Neurology. 2006; 63(10):1427-32. [DOI:10.1001/arch- neur.63.10.1427] [PMID] [PMCID]
[2] McMonagle P, Deering F, Berliner Y, Kertesz A. The cognitive pro- file of posterior cortical atrophy. Neurology. 2006; 66(3):331-8. [DOI:10.1212/01.wnl.0000196477.78548.db] [PMID]
[3] Snowden JS, Stopford CL, Julien CL, Thompson JC, Davidson Y, Gibbons L, et al. Cognitive phenotypes in Alzheimer’s disease and genetic risk. Cortex. 2007; 43(7):835-45. [DOI:10.1016/S0010- 9452(08)70683-X] [PMID]
[4] Mendez MF, Ghajarania M, Perryman KM. Posterior cortical atro- phy: Clinical characteristics and differences compared to Alzhei- mer’s disease. Dementia and Geriatric Cognitive Disorders. 2002; 14(1):33-40. [DOI:10.1159/000058331] [PMID]
[5] Tang-Wai DF, Graff-Radford NR, Boeve BF, Dickson DW, Parisi JE, Crook R, et al. Clinical, genetic, and neuropathologic characteris- tics of posterior cortical atrophy. Neurology. 2004; 63(7):1168-74. [DOI:10.1212/01.WNL.0000140289.18472.15] [PMID]
[6] Isella V, Villa G, Mapelli C, Ferri F, Appollonio IM, Ferrarese C. 2014. The neuropsychiatric profile of posterior cortical atrophy. Journal of Geriatric Psychiatry and Neurology. 2015; 28(2):136-44. [DOI:10.1177/0891988714554713] [PMID]
[7] Campbell JJ, Ngo G. Risperidone treatment of complex hallucina- tions in a patient with posterior cortical atrophy. The Journal of Neuropsychiatry and Clinical Neurosciences. 2008; 20(3):378-9. [DOI:10.1176/jnp.2008.20.3.378] [PMID]
[8] Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Tang-Wai DF, Dru- bach DA, et al. Visual hallucinations in posterior cortical atrophy. Archives of Neurology. 2006; 63(10):1427-32. [DOI:10.1001/arch- neur.63.10.1427] [PMID] [PMCID]
| Files | ||
| Issue | Vol 6 No 5 (2021): September-October | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/crcp.v6i5.8381 | |
| Keywords | ||
| Agnosia Atrophy Alzheimer disease Dementia | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Aghamollaii V, Fathollahzadeh Noor S, Bidaki R, Agah E. Posterior Cortical Atrophy With Interesting Presentation: Case Reports. CRCP. 2022;6(5):205-209.
