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Although the presence of intravesical foreign body is not a rare finding, orthopedic screw penetration into the urinary bladder as a complication of the  internal  fixation  of  femoral  neck  fractures  is  extremely  rare.  We describe an 83-year-old man experiencing spontaneous penetration of a cannulated screw into the urinary bladder neck, 16 years after the internal fixation surgery for his femoral neck fracture.

Interferon (IFN) beta is the most widely prescribed disease-modifying drug for multiple sclerosis (MS). However, some adverse reactions are observed in course of IFN-beta therapy. This article presents two cases of female patients diagnosed with relapsing-remitting MS who developed inflammatory musculoskeletal manifestations, following IFN-beta 1a therapy. In the first patient recurrent arthritis developed a week after initiation of IFN-beta, which improved few weeks after a switch to glatiramer acetate. The second patient developed recurrent arthritis 1 month after IFN-beta 1a therapy who suffered painful arthritis despite discontinuation of the medication. Both patients were seropositive for anti- cyclic citrullinated  peptide;  the first  patient  was a  positive  rheumatoid factor (RF) and the second patient was both positive RF and anti-Ro. The role of IFN-beta in the setting of inflammatory musculoskeletal disease remains unclear. To minimize its side effects, review of these antibodies may be required in patients who are candidates for this therapy.

Sarcoidosis is an inflammatory disorder characterized by the presence of noncaseating granulomas. Sarcoidosis can affect any organ in the body. As we know lung is most commonly affected but other organs such as liver, skin, eye and spleen could be involved. Here we report an interesting case of hepatic and splenic sarcoidosis in 55 year old woman suffered from epigastric pain, weight loss and constipation due to hypercalcemia.

We present a girl afflicted by Fasciola hepatica who was firstly considered to have other causes of jaundice and abdominal pain;however, she had eosinophilia. The clinicians initially ruled out the possibility parasitic infection via having one negative stool examination. According to the epidemiologic characteristics of the region, the patient belonged to hypereosinophilia and hyper IgE; we repeated the stool exam 3 times and the experienced parasitologist confirmed the diagnosis.

A 38-year-old man came to outpatient clinic complaining of a new-onset pain of his right buttock which has caused him to limp. Since six months ago, the pain had involved in order his cervical spine, ribs, sternum andthoracic spine, and left them deformed. He also had constitutional symptoms and significant weight loss. On physical examination, there was a limited chest expansion, positive Schober’s test, and multiple tender bony bumps along the ribs, costosternal and costochondral junctions. Lab tests showed anemia, elevated ESR, normal level of serum calcium, and creatinine, and 1+ protein in U/A. Serum protein electrophoresis was unexceptional. The imaging of the patient changed the diagnostic path. This article describes a deceptive visage of multiple myeloma presenting itself in the clothing of ankylosing spondylitis.

Systemic lupus erythematosus (SLE) is a chronic inflammatory disorderwith unknown etiology which can involve various organs in the body. The most common symptoms of this disease are constitutional symptoms along with skin rashes, arthritis, nephrologic, and hematologic manifestations. Acute pancreatitis is an unusual presentation of SLE. Here, we report an interesting case SLE who suffered from fever, weakness, abdominal pain, and weight loss. Finally, lupuspancreatitis was diagnosed based on her symptoms, laboratory, and imaging findings.

Primary Tuberculous Pyomyositis is a rare manifestation of musculoskeletal tuberculosis especially in immunocompetent individuals without a focus of tuberculosis in the body and the underlying bone disease [1]. We describe a 45 years-old incarcerated immunocompetant man with nontraumatic wound of right thumb since 9 months ago. The diagnosis of tuberculousdactylitis was based on positive acid fast bacilli using Ziehl-Neelson staining and Histopathology from involved skin.

This report describes a case of spinal canal stenosis at L4-L5 level andurinary incontinence (UI). An elderly woman was referred to a pain clinicwith persistent pain in low back and both lower limbs specially left leg. She complained of UI since 2 months before in a progressive manner as well. Because of progressive nature of her symptoms, physicians decided to refer her for surgery promptly; however, her cardiologic consult was not satisfactory, and surgery risk was reported significant. Physicians began symptomatic therapy and unexpectedly most of her symptoms were improved even her UI.

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